Functional segregation of cortical language areas by sentence repetition
| Autor: | Denis LeBihan, Stanislas Dehaene, Aurélie Campagne, Ghislaine Dehaene-Lambertz, Isabelle Denghien, Guillaume P. Dehaene, Jean-Baptiste Poline, Christophe Pallier, Mariano Sigman, Philippe Ciuciu, Jean-Luc Anton, Antoinette Jobert |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Male Speech recognition Auditory cortex behavioral disciplines and activities Functional Laterality Superior temporal gyrus Gyrus Neural Pathways medicine Humans Temporal dynamics of music and language Attention Radiology Nuclear Medicine and imaging Habituation Research Articles Language Cerebral Cortex Brain Mapping Language Tests Radiological and Ultrasound Technology Repetition (rhetorical device) Verbal Behavior Superior temporal sulcus Magnetic Resonance Imaging Temporal Lobe Frontal Lobe Expressed Emotion medicine.anatomical_structure Neurology Cerebrovascular Circulation Speech Perception Female Neurology (clinical) Nerve Net Anatomy Psychology psychological phenomena and processes Sentence Cognitive psychology |
| Zdroj: | Hum Brain Mapp |
| ISSN: | 1097-0193 1065-9471 |
| DOI: | 10.1002/hbm.20250 |
| Popis: | The functional organization of the perisylvian language network was examined using a functional MRI (fMRI) adaptation paradigm with spoken sentences. In Experiment 1, a given sentence was presented every 14.4 s and repeated two, three, or four times in a row. The study of the temporal properties of the BOLD response revealed a temporal gradient along the dorsal-ventral and rostral- caudal directions: From Heschl's gyrus, where the fastest responses were recorded, responses became increasingly slower toward the posterior part of the superior temporal gyrus and toward the temporal poles and the left inferior frontal gyrus, where the slowest responses were observed. Repetition induced a decrease in amplitude and a speeding up of the BOLD response in the superior temporal sulcus (STS), while the most superior temporal regions were not affected. In Experiment 2, small blocks of six sentences were presented in which either the speaker voice or the linguistic content of the sentence, or both, were repeated. Data analyses revealed a clear asymmetry: While two clusters in the left superior temporal sulcus showed identical repetition suppression whether the sentences were produced by the same speaker or different speakers, the homologous right regions were sensitive to sentence repetition only when the speaker voice remained constant. Thus, hemispheric left regions encode linguistic content while homologous right regions encode more details about extralinguistic features like speaker voice. The results demonstrate the feasibility of using sentence-level adaptation to probe the functional organization of cortical language areas. Hum Brain Mapp 27:360 -371, 2006. © 2006 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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