Ultrastructural evaluation of mid-dermal elastolysis
| Autor: | W. P. D. Su, B. D. Zelickson, E. J. Gagne, A. F. Fransway, C. B. Harmon |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Dermal elastolysis Histology Dermatology Degeneration (medical) Skin Diseases Pathology and Forensic Medicine Necrosis Dermis Biopsy medicine Humans Skin pathology Electron microscopic Skin integumentary system medicine.diagnostic_test business.industry Anatomy Middle Aged Elastic Tissue medicine.anatomical_structure Ultrastructure Female business Elastic fiber |
| Zdroj: | Journal of cutaneous pathology. 21(3) |
| ISSN: | 0303-6987 |
| Popis: | Mid-dermal elastolysis is a well-defined clinical and histopathologic entity manifested by fine wrinkling of the skin and a mid-dermal loss of elastic fibers. Ultrastructural and histologic studies were performed in an attempt to better define the cause of the elastolytic process. Biopsy specimens from the lesions of 3 patients with mid-dermal elastolysis were studied at light and electron microscopic levels. Ultrastructural evidence of normal elastic fiber engulfment by activated macrophages was observed; however, some fields also demonstrated envelopment of abnormally degenerated elastic tissue. Although there are many potential causes of this degeneration, photodistribution of the lesions suggests that ultraviolet damage is a primary inciting factor. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text