Removal of Small, Asymptomatic Kidney Stones and Incidence of Relapse

Autor: Mathew D. Sorensen, Jonathan D. Harper, Michael S. Borofsky, Tariq A. Hameed, Kimberly J. Smoot, Barbara H. Burke, Branda J. Levchak, James C. Williams, Michael R. Bailey, Ziyue Liu, James E. Lingeman
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: N Engl J Med
Popis: BACKGROUND: The benefits of removing small (≤6 mm), asymptomatic kidney stones endoscopically is unknown. Current guidelines leave such decisions to the urologist and the patient. A prospective study involving older, nonendoscopic technology and some retrospective studies favor observation. However, published data indicate that about half of small renal stones left in place at the time that larger stones were removed caused other symptomatic events within 5 years after surgery. METHODS: We conducted a multicenter, randomized, controlled trial in which, during the endoscopic removal of ureteral or contralateral kidney stones, remaining small, asymptomatic stones were removed in 38 patients (treatment group) and were not removed in 35 patients (control group). The primary outcome was relapse as measured by future emergency department visits, surgeries, or growth of secondary stones. RESULTS: After a mean follow-up of 4.2 years, the treatment group had a longer time to relapse than the control group (P
Databáze: OpenAIRE