Suppression of PHA-stimulated lymphocyte transformation in cynomolgus monkeys following infection with Coxiella burnetii

Autor: J. C. Gonder, R. A. Kishimoto
Rok vydání: 1979
Předmět:
Zdroj: Canadian Journal of Microbiology. 25:949-952
ISSN: 1480-3275
0008-4166
DOI: 10.1139/m79-145
Popis: Phytohemagglutin-induced blastogenesis of peripheral blood lymphocytes from cynomolgus monkeys infected with Coxiella burnetii was suppressed between 14 and 28 days after infection. Lymphocytes became responsive to PHA again on day 35 with an increase in stimulation index when cultured with specific antigens. In contrast, production of specific humoral antibodies was not diminished during the acute and early convalescent stages of infection. (Author)
Databáze: OpenAIRE