Cyclodextrin nanoassemblies: a promising tool for drug delivery
| Autor: | Cédric Gervaise, Catherine Sarazin, Florence Djedaïni-Pilard, Aurélien L. Furlan, Véronique Bonnet |
|---|---|
| Přispěvatelé: | Génie Enzymatique et Cellulaire (GEC), Université de Technologie de Compiègne (UTC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 (LG2A ), Institut de Chimie du CNRS (INC)-Université de Picardie Jules Verne (UPJV)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2015 |
| Předmět: |
[SDV]Life Sciences [q-bio]
Supramolecular chemistry Nanoparticle Nanotechnology 02 engineering and technology [CHIM.THER]Chemical Sciences/Medicinal Chemistry Gene delivery 010402 general chemistry 01 natural sciences Drug Delivery Systems Drug Stability Drug Discovery Amphiphile [CHIM]Chemical Sciences Humans Nanodevice Pharmacology chemistry.chemical_classification Cyclodextrins Drug Carriers Cyclodextrin technology industry and agriculture Gene Transfer Techniques 021001 nanoscience & nanotechnology 0104 chemical sciences [CHIM.POLY]Chemical Sciences/Polymers [SDV.SP.PG]Life Sciences [q-bio]/Pharmaceutical sciences/Galenic pharmacology chemistry Delayed-Action Preparations Drug delivery Nanoparticles lipids (amino acids peptides and proteins) Self-assembly 0210 nano-technology |
| Zdroj: | Drug Discovery Today Drug Discovery Today, Elsevier, 2015, 20, pp.1120-1126 Drug Discovery Today, Elsevier, 2015, 20 (9), pp.1120-1126. ⟨10.1016/j.drudis.2015.05.008⟩ |
| ISSN: | 1878-5832 1359-6446 |
| Popis: | International audience; Among the biodegradable and nontoxic compounds that can form nanoparticles for drug delivery, amphiphilic cyclodextrins are very promising. Apart from ionic cyclodextrins, which have been extensively studied and reviewed because of their application in gene delivery, our purpose is to provide a clear description of the supramolecular assemblies of nonionic amphiphilic cyclodextrins, which can form nanoassemblies for controlled drug release. Moreover, we focus on the relationship between their structure and physicochemical characteristics, which is crucial for self assembly and drug delivery. We also highlight the importance of the nanoparticle technology preparation for the stability and application of this nanodevice. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect