Effect of Lysogeny on Serum Sensitivity
| Autor: | L. S. Baron, Lissa A. Ahl, Louis H. Muschel |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 1968 |
| Předmět: |
Serotype
Genetics Microbial Blood Bactericidal Activity Shigella dysenteriae viruses Infection and Immunity Biology medicine.disease_cause Microbiology Coliphages Salmonella Lysogenic cycle Pseudomonas medicine Escherichia coli Shigella Bacteriophages Molecular Biology Lysogeny Prophage Immunity biology.organism_classification Blood Salmonella Phages Bacteria |
| Popis: | When Escherichia coli K-12 was infected with λ phage and mutants of λ characterized by the production of temperature-sensitive repressors, the lysogenic bacteria were significantly more resistant to normal serum than the uninfected organisms. Infection of E. coli K-12 with a lambdoid phage, φ80, whose prophage attachment site is different from that of λ, did not result in a detectable change in serum resistance. Similarly, infection with certain Pseudomonas and Shigella phages caused no detectable differences in serum resistance. Finally, the well-known conversion of the Salmonella anatum serotype to S. newington by E 15 phage indicated that, despite the relatively greater roughness of S. anatum, S. newington was more sensitive to normal serum than S. anatum . Thus, the effects of lysogeny on the sensitivity of bacteria to the bactericidal action of serum mediated by the complement system may be quite variable. |
| Databáze: | OpenAIRE |
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