Cell interactions in collective cell migration
| Autor: | Denise J. Montell, James A. Mondo, Joseph P. Campanale, Abhinava K. Mishra |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Cell type
Cell Motility Cell Communication Biology 03 medical and health sciences 0302 clinical medicine Cell Movement Development at A Glance Neoplasms medicine Coordinated movement Animals Humans Neoplasm Metastasis Molecular Biology 030304 developmental biology 0303 health sciences Collective cell migration Contact inhibition Cell migration Chemotaxis medicine.anatomical_structure 030220 oncology & carcinogenesis Neuroscience Developmental Biology |
| Zdroj: | Development |
| ISSN: | 1477-9129 0950-1991 |
| DOI: | 10.1242/dev.172056 |
| Popis: | Collective cell migration is the coordinated movement of a physically connected group of cells and is a prominent driver of development and metastasis. Interactions between cells within migrating collectives, and between migrating cells and other cells in the environment, play key roles in stimulating motility, steering and sometimes promoting cell survival. Similarly, diverse heterotypic interactions and collective behaviors likely contribute to tumor metastasis. Here, we describe a sampling of cells that migrate collectively in vivo, including well-established and newer examples. We focus on the under-appreciated property that many – perhaps most – collectively migrating cells move as cooperating groups of distinct cell types. |
| Databáze: | OpenAIRE |
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