Acute-onset smell and taste disorders in the context of COVID-19: a pilot multicentre polymerase chain reaction based case-control study
| Autor: | Araceli Alonso-Canovas, Juan Luis Chico-García, Enric Monreal, Jose Luis Cortes-Cuevas, Jorge Gómez‐Corral, Jaime Masjuan, Fernando Rodríguez-Jorge, Javier Martínez‐Poles, Álvaro Beltrán-Corbellini, Elena Natera-Villalba, Ana Gomez-Lopez, Juan Carlos Galán, Jesús Porta-Etessam, Paloma Parra-Díaz, Claudio Fragola‐Arnau |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Short Communication Clinical Neurology Anosmia Context (language use) Polymerase Chain Reaction coronavirus infection 03 medical and health sciences Olfaction Disorders Taste Disorders 0302 clinical medicine Internal medicine Surveys and Questionnaires Influenza Human medicine Humans 030212 general & internal medicine Letters to the Editor Pandemics Aged Respiratory tract infections business.industry Incidence (epidemiology) Incidence Case-control study COVID-19 case–control study smell disorders Odds ratio Ageusia Middle Aged PCR Neurology Taste disorder Case-Control Studies Female Neurology (clinical) Self Report medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | European Journal of Neurology |
| ISSN: | 1468-1331 |
| Popis: | BACKGROUND AND PURPOSE: Specific respiratory tract infections, including COVID-19, may cause smell and/or taste disorders (STDs) with increased frequency. The aim was to determine whether new-onset STDs are more frequent amongst COVID-19 patients than influenza patients. METHOD: This was a case-control study including hospitalized patients of two tertiary care centres. Consecutive patients positive for COVID-19 polymerase chain reaction (cases) and patients positive for influenza polymerase chain reaction (historical control sample) were assessed during specific periods, employing a self-reported STD questionnaire. RESULTS: Seventy-nine cases and 40 controls were included. No significant differences were found in basal features between the two groups. New-onset STDs were significantly more frequent amongst cases (31, 39.2%) than in the control group (5, 12.5 %) [adjusted odds ratio 21.4 (2.77-165.4, P = 0.003)]. COVID-19 patients with new-onset STDs were significantly younger than COVID-19 patients without STDs (52.6 ± 17.2 vs. 67.4 ± 15.1, P |
| Databáze: | OpenAIRE |
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