Long-term outcomes after coronary artery bypass surgery in patients with diabetes
| Autor: | Tomas A Axelsson, Karl Andersen, Linda O Arnadottir, Tomas Gudbjartsson, Solveig Helgadottir, Andri Wilberg Orrason, Jonas A. Adalsteinsson, Dadi Helgason, Hera Johannesdottir |
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| Rok vydání: | 2019 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Population Iceland Comorbidity Coronary Artery Disease 030204 cardiovascular system & hematology 03 medical and health sciences Coronary artery bypass surgery 0302 clinical medicine Postoperative Complications Internal medicine Diabetes mellitus medicine Diabetes Mellitus Humans 030212 general & internal medicine Coronary Artery Bypass education Aged Retrospective Studies education.field_of_study business.industry Proportional hazards model Incidence Hazard ratio Odds ratio medicine.disease Survival Rate Treatment Outcome Cardiology Surgery Female Cardiology and Cardiovascular Medicine business Body mass index Kidney disease Follow-Up Studies Forecasting |
| Zdroj: | Interactive cardiovascular and thoracic surgery. 30(5) |
| ISSN: | 1569-9285 |
| Popis: | OBJECTIVES Our aim was to investigate the outcome of patients with diabetes undergoing coronary artery bypass grafting (CABG) surgery in a whole population with main focus on long-term mortality and complications. METHODS This was a nationwide retrospective analysis of all patients who underwent isolated primary CABG in Iceland between 2001 and 2016. Overall survival together with the composite end point of major adverse cardiac and cerebrovascular events was compared between patients with diabetes and patients without diabetes during a median follow-up of 8.5 years. Multivariable regression analyses were used to evaluate the impact of diabetes on both short- and long-term outcomes. RESULTS Of a total of 2060 patients, 356 (17%) patients had diabetes. Patients with diabetes had a higher body mass index (29.9 vs 27.9 kg/m2) and more often had hypertension (83% vs 62%) and chronic kidney disease (estimated glomerular filtration rate ≤60 ml/min/1.73 m2, 21% vs 14%). Patients with diabetes had an increased risk of operative mortality [odds ratio 2.52, 95% confidence interval (CI) 1.27–4.80] when adjusted for confounders. 5-Year overall survival (85% vs 91%, P CONCLUSIONS Patients with diabetes have significantly lower survival after CABG, both within 30 days and during long-term follow-up. |
| Databáze: | OpenAIRE |
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