Chest X-ray findings in a large cohort of 1117 patients with SARS-CoV-2 infection: a multicenter study during COVID-19 outbreak in Italy
| Autor: | Sandro Magnani, Giuseppe Cipolla, Sonia Ippolito, Anna Maria Ierardi, Gianpaolo Carrafiello, Francesco Blasi, Barbara Pirrò, Guido Plensich, Chiara Villa, Maria Carmela Andrisani, Giacomo Grasselli, Stefano Fusco, Antonio Scamporrino, Luigia Scudeller, Andrea Coppola, Letizia Di Meglio, Andrea Ianniello, Alice Scarabelli, Emanuele Catena, Mario Petrillo, Antonio Pesenti, Alberto Cazzulani, Massimo Galli, Giuliano Rizzardini, Stefano Aliberti, Guglielmo Damiani, Genti Xhepa, Valentina Vespro, Andrea Gori, Elvira Stellato, Matteo Agostino Orlandi |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Coronavirus disease 2019 (COVID-19) Adolescent Radiography Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Thoracic Real-Time Polymerase Chain Reaction 030218 nuclear medicine & medical imaging Cohort Studies 03 medical and health sciences 0302 clinical medicine McNemar's test Diagnosis medicine Internal Medicine Humans Pandemics Aged Aged 80 and over Lung business.industry Outbreak COVID-19 Middle Aged Large cohort Im - Original medicine.anatomical_structure Italy 030220 oncology & carcinogenesis Cohort Emergency Medicine Female Radiography Thoracic Radiology business |
| Zdroj: | Internal and Emergency Medicine |
| ISSN: | 1970-9366 |
| Popis: | To describe radiographic key patterns on Chest X-ray (CXR) in patients with SARS-CoV-2 infection, assessing the prevalence of radiographic signs of interstitial pneumonia. To evaluate pattern variation between a baseline and a follow-up CXR. 1117 patients tested positive for SARS-CoV-2 infection were retrospectively enrolled from four centers in Lombardy region. All patients underwent a CXR at presentation. Follow-up CXR was performed when clinically indicated. Two radiologists in each center reviewed images and classified them as suggestive or not for interstitial pneumonia, recording the presence of ground-glass opacity (GGO), reticular pattern or consolidation and their distribution. Pearson’s χ2 test for categorical variables and McNemar test (χ2 for paired data) were performed. Patients mean age 63.3 years, 767 were males (65.5%). The main result is the large proportion of positive CXR in COVID-19 patients. Baseline CXR was positive in 940 patients (80.3%), with significant differences in age and sex distribution between patients with positive and negative CXR. 382 patients underwent a follow-up CXR. The most frequent pattern on baseline CXR was the GGO (66.1%), on follow-up was consolidation (53.4%). The most common distributions were peripheral and middle-lower lung zone. We described key-patterns and their distribution on CXR in a large cohort of COVID-19 patients: GGO was the most frequent finding on baseline CXR, while we found an increase in the proportion of lung consolidation on follow-up CXR. CXR proved to be a reliable tool in our cohort obtaining positive results in 80.3% of the baseline cases. |
| Databáze: | OpenAIRE |
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