Elevated serum synuclein-gamma in patients with gastrointestinal and esophageal carcinomas
| Autor: | Caiyun Liu, Chengchao Shou, Lin Meng, Like Qu, Huachong Ma, Jian Wu |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty CA-19-9 Antigen Esophageal Neoplasms Colorectal cancer Enzyme-Linked Immunosorbent Assay Adenocarcinoma Gastroenterology Sensitivity and Specificity Serology Young Adult Carcinoembryonic antigen gamma-Synuclein Predictive Value of Tests Stomach Neoplasms Internal medicine Carcinoma medicine Biomarkers Tumor Humans Clinical significance Early Detection of Cancer Aged Aged 80 and over Analysis of Variance Hepatology biology business.industry Cancer General Medicine Esophageal cancer Middle Aged medicine.disease Prognosis Carcinoembryonic Antigen Neoplasm Proteins Up-Regulation ROC Curve Case-Control Studies biology.protein Carcinoma Squamous Cell Biomarker (medicine) Female business Colorectal Neoplasms |
| Zdroj: | Hepato-gastroenterology. 59(119) |
| ISSN: | 0172-6390 |
| Popis: | BACKGROUND/AIMS We aimed to evaluate whether elevated serum synuclein-gamma levels were of clinical significance as a serological marker in cancer diagnosis and monitoring. METHODOLOGY Pre-treatment serum synuclein-gamma levels of patients with gastrointestinal and esophageal squamous cell carcinomas, benign disease and healthy controls were analyzed by a specific sandwich ELISA for synuclein-gamma. RESULTS Statistically significant differences in serum synuclein-gamma levels between patients with colo rectal cancer, gastric adenocarcinomas, esophageal cancer and healthy individuals were observed (p |
| Databáze: | OpenAIRE |
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