Tissue Plasminogen Activator in the Lens
| Autor: | Ramesh C. Tripathi, Brenda J. Tripathi, John D. Geanon |
|---|---|
| Rok vydání: | 1988 |
| Předmět: |
genetic structures
Positive reaction Enzyme-Linked Immunosorbent Assay Lens epithelium Tissue plasminogen activator law.invention Extracellular matrix Cellular and Molecular Neuroscience Dogs law Lens Crystalline medicine Animals Tissue Distribution Lens capsule Chemistry Haplorhini General Medicine Immunohistochemistry Molecular biology eye diseases Sensory Systems Lens (optics) Ophthalmology Tissue Plasminogen Activator Cattle sense organs medicine.drug |
| Zdroj: | Ophthalmic Research. 20:160-163 |
| ISSN: | 1423-0259 0030-3747 |
| DOI: | 10.1159/000266578 |
| Popis: | Biochemical analyses of normal lenses from monkey, dog and calf eyes revealed significant levels of tissue plasminogen activator (t-PA). By immunohistochemistry, a positive reaction product for t-PA was seen, in descending order of staining intensity, in the central epithelium, equatorial epithelium, superficial fibers of the anterior cortex, and anterior capsule of both human and monkey lenses. The possible functions of t-PA in the normal 801s include regulation of deformation that occurs in the anterior lens epithelium and fibers during the process of accommodation, and the destructive remodeling of the extracellular matrix including the lens capsule. |
| Databáze: | OpenAIRE |
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