The Mammalian Urine Concentrating Mechanism: Hypotheses and Uncertainties

Autor:	Harold E. Layton, Anita T. Layton, William H. Dantzler, Thomas L. Pannabecker
Rok vydání:	2009
Předmět:	Kidney Medulla Kidney Physiology Mechanism (biology) Extramural Urine Biology Rats Cell biology Kidney Tubules medicine.anatomical_structure Biochemistry Models Animal Loop of Henle medicine Animals Blood Vessels Inner medulla
Zdroj:	Physiology. 24:250-256
ISSN:	1548-9221 1548-9213
Popis:	The urine concentrating mechanism of the mammalian kidney, which can produce a urine that is substantially more concentrated than blood plasma during periods of water deprivation, is one of the enduring mysteries in traditional physiology. Owing to the complex lateral and axial relationships of tubules and vessels, in both the outer and inner medulla, the urine concentrating mechanism may only be fully understood in terms of the kidney’s three-dimensional functional architecture and its implications for preferential interactions among tubules and vessels.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efa76b20742e6b8a9e655ff62b0c0402 https://doi.org/10.1152/physiol.00013.2009 Zobrazit plný text záznamu