Effective control of SARS-CoV-2 transmission in Wanzhou, China

Autor: Xiaojun Tang, Chao Luo, Cheng Yong Yang, Wei Wang, Ailong Huang, Bo Wu, Bin Peng, Yaoyue Hu, Qiuling Shi, Kun Su, Xiao Ni Zhong, Yong Zhang, Fan Zhang, Jing Fu Qiu, Benjamin Anderson
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Nature Medicine
ISSN: 1546-170X
1078-8956
DOI: 10.1038/s41591-020-01178-5
Popis: The effectiveness of control measures to contain coronavirus disease 2019 (COVID-19) in Wanzhou, China was assessed. Epidemiological data were analyzed for 183 confirmed COVID-19 cases and their close contacts from five generations of transmission of severe acute respiratory syndrome coronavirus 2 throughout the entire COVID-19 outbreak in Wanzhou. Approximately 67.2% and 32.8% of cases were symptomatic and asymptomatic, respectively. Asymptomatic and presymptomatic transmission accounted for 75.9% of the total recorded transmission. The reproductive number was 1.64 (95% confidence interval: 1.16-2.40) for G1-to-G2 transmission, decreasing to 0.31-0.39 in later generations, concomitant with implementation of rigorous control measures. Substantially higher infection risk was associated with contact within 5 d after the infectors had been infected, frequent contact and ≥8 h of contact duration. The spread of COVID-19 was effectively controlled in Wanzhou by breaking the transmission chain through social distancing, extensive contact tracing, mass testing and strict quarantine of close contacts.
Databáze: OpenAIRE
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