Bone Mineral Density in Type 2 Diabetes Patients with Charcot Arthropathy
| Autor: | Mona Abdelsalam, Yara M. Eid, Rana El Hilaly, Hussein A. El Oraby, Heba A. Marzouk |
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| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Endocrinology Diabetes and Metabolism Osteoporosis Type 2 diabetes Gastroenterology Diabetes Complications Endocrinology Bone Density Risk Factors Internal medicine Diabetes mellitus Arthropathy medicine Humans Femur Bone mineral Glycated Hemoglobin business.industry medicine.disease Diabetic foot Osteopenia Diabetes Mellitus Type 2 Female Arthropathy Neurogenic business |
| Zdroj: | Current diabetes reviews. 15(5) |
| ISSN: | 1875-6417 |
| Popis: | Introduction: Charcot arthropathy is one of the disabling diabetes complications. There are enigmatic areas concerning its underlying pathophysiology and risk predictors. Osteoporosis and local osteopenia have been postulated to have a role in Charcot arthropathy development, but it is still controversial. Background: The study aims to compare bone mineral density among type 2 diabetics with and without Charcot arthropathy. Methods: Two groups with type 2 diabetes participated in this study; Group I [30] patients with Charcot arthropathy while Group II [30] patients without charcot arthropathy. All patients underwent full clinical examination and complete history taking with special emphasis on foot problems. Laboratory investigations were done that included fasting blood sugar, postprandial blood sugar, glycosylated hemoglobin, serum calcium, serum phosphorus, and alkaline phosphatase. All patients underwent MRI for both feet and dual energy X-ray absorptiometry scan of the lumbar spine and femur. The demographic data, clinical data, the presence or absence of comorbidities and bone mineral density were compared for both groups. Results: Bone mineral density was significantly lower in Group I than Group II with median lumber T score (-0.15, 1.99 p Conclusion: Bone mineral density is lower in patients with Charcot arthropathy with female gender and Femur T score as risk predictors. Peripheral arterial disease shows greater incidence in Charcot patients than was previously reported. |
| Databáze: | OpenAIRE |
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