Chemical Composition, Enantiomeric Analysis, AEDA Sensorial Evaluation and Antifungal Activity of the Essential Oil from the Ecuadorian Plant Lepechinia mutica Benth (Lamiaceae)
| Autor: | Cecila Cagliero, Gianluca Gilardoni, José Vinicio Montesinos, Miriam Jácome, Marinella Rodolfi, Jorge Ramírez, M. Guglielminetti, Carlo Bicchi, Giovanni Vidari |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Antifungal Agents
Chromatography Gas Monoterpene Bioengineering Sesquiterpene 01 natural sciences Biochemistry Gas Chromatography-Mass Spectrometry law.invention chemistry.chemical_compound Trichophyton law Botany Candida albicans Oils Volatile Microsporum lepechinia mutica ecuador enantiomeric analysis gas chromatography-olfactometry antifungal activity gas-chromatography antimicrobial activity chamaedryoides identification odorants flavor Food science Molecular Biology Chemical composition Essential oil Aroma Lamiaceae biology 010405 organic chemistry Chemistry Stereoisomerism General Chemistry General Medicine biology.organism_classification 0104 chemical sciences Plant Leaves 010404 medicinal & biomolecular chemistry Molecular Medicine Ecuador Seasons Enantiomer Lepechinia mutica |
| Popis: | This study describes the GC-FID, GC-MS, GC-O, and enantioselective GC analysis of the essential oil hydrodistilled from leaves of Lepechinica mutica (Lamiaceae), collected in Ecuador. GC-FID and GC-MS analyses allowed the characterization and quantification of 79 components, representing 97.3% of the total sample. Sesquiterpene hydrocarbons (38.50%) and monoterpene hydrocarbons (30.59%) were found to be the most abundant volatiles, while oxygenated sesquiterpenes (16.20%) and oxygenated monoterpenes (2.10%) were the minor components. In order to better characterize the oil aroma, the most important odorants, from the sensorial point of view, were identified by Aroma Extract Dilution Analysis (AEDA) GC-O. They were α-pinene, β-phellandrene, and dauca-5,8-diene, exhibiting the characteristic woody, herbaceus and earthy odors, respectively. Enantioselective GC analysis of L. mutica essential oil revealed the presence of twelve couples and two enantiomerically pure chiral monoterpenoids. Their enantiomeric excesses were from a few percent units to 100%. Moreover, the essential oil exhibited moderate in vitro activity against five fungal strains, being especially effective against M. canis, which is a severe zoophilic dermatophyte causal agent of pet and human infections. This article is protected by copyright. All rights reserved. |
| Databáze: | OpenAIRE |
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