Measuring forearm bone density instead of lumbar spine bone density improves the sensitivity of diagnosing osteoporosis in older adults with cardiovascular diseases: Data from SARCOS study
| Autor: | Elaine Azevedo, Angela Tavares Paes, Amanda Diniz Kimura, Valdir Ambrosio, Alberto Frisoli |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
Aortic calcification medicine.medical_specialty Bone density Endocrinology Diabetes and Metabolism Osteoporosis Distal forearm BMD Diseases of the musculoskeletal system Elderly Internal medicine Full Length Article medicine Orthopedics and Sports Medicine Femur Femoral neck Proximal femur business.industry medicine.disease musculoskeletal system medicine.anatomical_structure RC925-935 Forearm bone Lumbar spine business |
| Zdroj: | Bone Reports, Vol 15, Iss, Pp 101134-(2021) Bone Reports |
| ISSN: | 2352-1872 |
| Popis: | Introduction In older individuals with cardiovascular diseases, it has been challenging to diagnose osteoporosis due to aortic calcification and degenerative processes in the spine of older adults, especially in very old adults. Aim To assess whether the distal forearm BMD with the proximal femur BMD has greater sensitivity for the diagnosis of osteoporosis than the lumbar spine BMD with the proximal femur BMD. Methods We evaluated 515 older adults with cardiovascular disease from the SARCOS study and stratified them into under and over 80-year-old age groups and according to gender. Two diagnostic criteria were used to assess osteoporosis, SPF (lumbar spine and proximal femur BMD) and DFF (distal forearm and proximal femur BMD), which were compared with the multiple bone sites (MS) criteria (lumbar spine, distal radius, femoral neck, and total femur BMD). Results 43.9% were aged ≥80 years. Osteoporosis by SPF was diagnosed in 34% (n = 175), by DFF in 42.2% (n = 216), and by MS in 46.8% (n = 241). The characteristics of the three groups were similar. For every 100 older individuals with osteoporosis based on MS, 27 were not diagnosed by the SPF, and nine were not diagnosed by DFF (p = 0.001). The SPF did not diagnose osteoporosis in 23/100 in older adults aged Highlights • Diagnosis of osteoporosis (OP) in the elderly with cardiovascular disease is challenging. • We evaluated the sensitivity of distal forearm (DF) BMD vs. lumbar spine (LS) BMD. • LS BMD did not diagnose OP in 27/100, and DF BMD in 9/100 (p = 0.001). • LS BMD did not identify OP in 31/100, and DF BMD in 5/100 (p |
| Databáze: | OpenAIRE |
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