Assessment of the risk of Ebola virus transmission from bodily fluids and fomites
| Autor: | Pierre E. Rollin, Felix Kaducu, Anthony Sanchez, Jonathan S. Towner, Thomas G. Ksiazek, Scott F. Dowell, Matthew Lukwiya, Stuart T. Nichol, Daniel G. Bausch |
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| Rok vydání: | 2007 |
| Předmět: |
Filoviridae
medicine.disease_cause Virus Disease Outbreaks Ebola Hemorrhagic Fever Risk Factors medicine Immunology and Allergy Infection control Humans Uganda Viral shedding Mononegavirales Saliva Ebola virus biology business.industry Reverse Transcriptase Polymerase Chain Reaction Hemorrhagic Fever Ebola biology.organism_classification Ebolavirus Virology Survival Analysis Body Fluids Virus Shedding Hemorrhagic Fevers Infectious Diseases Fomites Immunology business |
| Zdroj: | The Journal of infectious diseases. 196 |
| ISSN: | 0022-1899 |
| Popis: | Although Ebola virus (EBOV) is transmitted by unprotected physical contact with infected persons, few data exist on which specific bodily fluids are infected or on the risk of fomite transmission. Therefore, we tested various clinical specimens from 26 laboratory-confirmed cases of Ebola hemorrhagic fever, as well as environmental specimens collected from an isolation ward, for the presence of EBOV. Virus was detected by culture and/or reverse-transcription polymerase chain reaction in 16 of 54 clinical specimens (including saliva, stool, semen, breast milk, tears, nasal blood, and a skin swab) and in 2 of 33 environmental specimens. We conclude that EBOV is shed in a wide variety of bodily fluids during the acute period of illness but that the risk of transmission from fomites in an isolation ward and from convalescent patients is low when currently recommended infection control guidelines for the viral hemorrhagic fevers are followed. |
| Databáze: | OpenAIRE |
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