Consumption of Whole-Grain Bread and Risk of Colorectal Cancer among Norwegian Women (the NOWAC Study)
| Autor: | Tonje Braaten, Guri Skeie, Anja Olsen, Cecilie Kyrø, Toril Bakken, Eiliv Lund |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Gerontology Colorectal cancer VDP::Medical disciplines: 700::Health sciences: 800::Nutrition: 811 Eating 0302 clinical medicine Risk Factors Epidemiology Prospective Studies Prospective cohort study Whole Grains Nutrition and Dietetics Norway Incidence Incidence (epidemiology) Hazard ratio proximal colon cohort Middle Aged Micronutrient Diet Records 030220 oncology & carcinogenesis Cohort Female women Colorectal Neoplasms lcsh:Nutrition. Foods and food supply medicine.medical_specialty bread lcsh:TX341-641 colorectal cancer Article 03 medical and health sciences Environmental health medicine Humans Aged 030109 nutrition & dietetics business.industry Feeding Behavior whole-grain prospective medicine.disease digestive system diseases Confidence interval Diet business Follow-Up Studies Food Science |
| Zdroj: | Nutrients; Volume 8; Issue 1; Pages: 40 Nutrients Nutrients, Vol 8, Iss 1, p 40 (2016) |
| ISSN: | 2072-6643 |
| Popis: | Published version. Source at http://doi.org/10.3390/nu8010040. License CC BY 4.0. There is evidence that consumption of foods containing dietary fiber decreases the risk of colorectal cancer (CRC). Whole grains contain dietary fiber, as well as a range of micronutrients and bioactive compounds, but the association between the consumption of whole grains and the risk of CRC remains less studied. The aim of the present study was to investigate the association between whole-grain bread consumption and CRC incidence among Norwegian women, using data from a prospective cohort study (the Norwegian Women and Cancer Study). Dietary intake was estimated from the food-frequency questionnaires of 78,254 women in the cohort (median age: 55 years), and these women were then followed up for CRC incidence. During the 9 years of median follow-up, 795 women were diagnosed with CRC (316 proximal, 193 distal, 218 rectal). Associations between whole-grain bread consumption and the risk of CRC (including colorectal subsites) were investigated using Cox proportional hazards regression models. When compared to the low consumption group, the hazard ratio for CRC was 0.89 (95% confidence interval (CI): 0.72–1.09) for the high consumption group and 0.86 (95% CI: 0.72–1.02) for the medium consumption group in a multivariable model. Overall, no association between whole-grain bread consumption and CRC was found. |
| Databáze: | OpenAIRE |
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