Effects of ascorbic acid supplementation on oxidative stress markers in healthy women following a single bout of exercise

Autor: Suwatsin Kittikunnathum, Wichuda Nak-on, Petcharee Yeethong, Chawannut Suknikorn, Manita Yimcharoen, Tracy G. Anthony, Piyawan Bunpo
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Blood Glucose
0301 basic medicine
Antioxidant
medicine.medical_treatment
Ascorbic Acid
medicine.disease_cause
chemistry.chemical_compound
0302 clinical medicine
Malondialdehyde
Vitamin C
Creatine Kinase
Cross-Over Studies
Nutrition and Dietetics
biology
Catalase
Ferric reducing ability of plasma
C-Reactive Protein
Female
lcsh:RC1200-1245
lcsh:Nutrition. Foods and food supply
Research Article
Adult
medicine.medical_specialty
lcsh:TX341-641
Creatine
Thiobarbituric Acid Reactive Substances
Oxidative stress markers
Superoxide dismutase
Young Adult
03 medical and health sciences
Muscle damage
Internal medicine
medicine
Humans
lcsh:Sports medicine
Exercise
Inflammation
Glutathione Peroxidase
030109 nutrition & dietetics
L-Lactate Dehydrogenase
Superoxide Dismutase
business.industry
030229 sport sciences
Ascorbic acid
Oxidative Stress
Endocrinology
Glucose
chemistry
Dietary Supplements
biology.protein
business
Biomarkers
Oxidative stress
Food Science
Zdroj: Journal of the International Society of Sports Nutrition, Vol 16, Iss 1, Pp 1-9 (2019)
Journal of the International Society of Sports Nutrition
ISSN: 1550-2783
DOI: 10.1186/s12970-019-0269-8
Popis: Background Ascorbic acid is a water-soluble chain breaking antioxidant. It scavenges free radicals and reactive oxygen species (ROS), which are produced during metabolic pathways. Exercise can produce an imbalance between ROS and antioxidants, leading to oxidative stress-related tissue damages. This study was designed to determine the effects of ascorbic acid supplementation on circulating biomarkers of oxidative stress and muscle damage following a single bout of exercise. Methods In a crossover design with a 1 wk. wash-out period, 19 healthy women performed 30 min moderate-intensity cycling after ingesting 1000 mg of ascorbic acid (AA) or placebo. Blood samples were taken immediately before, immediately after and 30 min post-exercise to determine plasma albumin, total protein, glucose, oxidative stress and muscle damage markers. Results Plasma albumin and total protein levels increased immediately after exercise in placebo alongside slight reductions in glucose (p = 0.001). These effects were absent in AA cohort. Ferric reducing ability of plasma and vitamin C levels in AA cohort significantly increased after exercise (p
Databáze: OpenAIRE
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