Pontine and thalamic influences on fluid rewards: III. Anticipatory contrast for sucrose and corn oil
| Autor: | Ralph Norgren, Patricia S. Grigson, Nu Chu Liang |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Male
Sucrose medicine.medical_specialty Time Factors Drinking Behavior Experimental and Cognitive Psychology Stimulus (physiology) Choice Behavior Article Rats Sprague-Dawley Food Preferences Behavioral Neuroscience chemistry.chemical_compound Saccharin Reward Thalamus Pons Internal medicine Reaction Time medicine Animals Analysis of Variance Motivation Dose-Response Relationship Drug Chemistry Rats Sham feeding Endocrinology Biochemistry Sweetening Agents Conditioning Operant Conditioning Corn Oil Ibotenic acid Corn oil |
| Zdroj: | Physiology & Behavior. 105:595-606 |
| ISSN: | 0031-9384 |
| DOI: | 10.1016/j.physbeh.2011.06.008 |
| Popis: | An anticipatory contrast effect (ACE) occurs when, across daily trials, an animal comes to respond less than normally to a first stimulus when it is followed shortly by a second, more preferred solution. Classically, ACE is studied using a low (L) concentration of saccharin or sucrose, followed by access to a higher (H) concentration of sucrose. Subjects in the control condition have two bouts of access to the weaker solution presented on the same schedule. The ACE is measured by the difference in intake of the first bout low solution between subjects in the low-low (L-L) vs. the low-high (L-H) conditions. Here we used this paradigm with sham feeding rats and determined that nutritional feedback was unnecessary for the development of ACE with two concentrations of sucrose or with two concentrations of corn oil. Next we showed that ibotenic acid lesions centered in the orosensory thalamus spared ACEs for both sucrose and corn oil. In contrast, lesions of the pontine parabrachial nuclei (PBN), the second central relay for taste in the rat, disrupted ACEs for both sucrose and corn oil. Although the sensory modalities needed for the oral detection of fats remain controversial, it appears that the PBN is involved in processing the comparison of disparate concentrations of sucrose and oil reward. |
| Databáze: | OpenAIRE |
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