Neurodevelopment in children with albinism
| Autor: | C. Gail Summers, Ann M. Holleschau, Beth R. Kutzbach, John T. MacDonald |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Visual acuity Adolescent Tandem gait Gross motor skill Visual impairment Visual Acuity Child Behavior Audiology Motor Activity Neuropsychological Tests Nervous System Surveys and Questionnaires Pervasive developmental disorder medicine Attention deficit hyperactivity disorder Humans Child business.industry medicine.disease Albinism Ocular Surgery Ophthalmology El Niño Reading Albinism Oculocutaneous Attention Deficit Disorder with Hyperactivity Motor Skills Child Preschool Albinism Female medicine.symptom business |
| Zdroj: | Ophthalmology. 115(10) |
| ISSN: | 1549-4713 |
| Popis: | Objectives To evaluate neurologic development in children with albinism. Design Observational cohort series. Participants and/or Controls Seventy-eight children with albinism, ages 4 to 18 years. Methods Parents completed a developmental questionnaire and were interviewed to evaluate their child for attention deficit hyperactivity disorder (ADHD) utilizing Diagnostic and Statistical Manual IV criteria. Sixty-five children underwent neurologic evaluation of balance and fine and gross motor movements. Results were compared with age-appropriate norms. Standardized reading tests were administered to 44 children. Each of 7 neurodevelopmental parameters were compared in terms of binocular best-corrected visual acuity (BCVA) using the nonparametric Wilcoxon rank-sum test. Main Outcome Measures Seven neurodevelopmental parameters were measured, including onset of walking, tandem gait, repetitive finger movements, sequential finger movements, standing on one foot, hopping on one foot, and throwing a ball overhand. School performance, reading performance, and presence of ADHD were also measured. Results The BCVA ranged from 20/20 to 20/800, with median of 20/150. A diagnosis of ADHD was present in 21.8% and pervasive developmental disorder was noted in three children (3.8%). No significant developmental delays were noted in the majority of children. Motor development was generally within the normal range and unaffected by severity of visual impairment. Parents reported that 82% performed at grade level in math and 74% at grade level in reading. Only 18% scored below average on standardized reading tests. Conclusions Most children with albinism have normal neurologic development despite visual impairment and increased prevalence of ADHD. Financial Disclosure(s) The authors have no proprietary or commercial interest in any materials discussed in this article. |
| Databáze: | OpenAIRE |
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