Chemical priming for spinal cord injury: a review of the literature. Part I—factors involved
| Autor: | Patrick R. Pritchard, Fatemeh B. Esfahani, Ketan Verma, Nicholas Theodore, R. Shane Tubbs, Aman Deep, Martin M. Mortazavi |
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| Rok vydání: | 2010 |
| Předmět: |
Nervous system
medicine.medical_specialty Cord Neurite business.industry General Medicine medicine.disease Spinal cord Neuroregeneration Nerve Regeneration medicine.anatomical_structure Anesthesia Peripheral nervous system Pediatrics Perinatology and Child Health medicine Animals Humans Nerve Growth Factors Neurology (clinical) Neurosurgery business Neuroscience Spinal cord injury Spinal Cord Injuries |
| Zdroj: | Child's Nervous System. 27:1297-1306 |
| ISSN: | 1433-0350 0256-7040 |
| DOI: | 10.1007/s00381-010-1364-y |
| Popis: | There are significant differences between the propensity of neural regeneration between the central and peripheral nervous systems. Following a review of the literature, we describe the role of growth factors, guiding factors, and neurite outgrowth inhibitors in the physiology and development of the nervous system as well as the pathophysiology of the spinal cord. We also detail their therapeutic role as well as those of other chemical substances that have recently been found to modify regrowth following cord injury. Multiple factors appear to have promising futures for the possibility of improving spinal cord injury following injury. |
| Databáze: | OpenAIRE |
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