Enhancement effect of p-iodophenol on gold nanoparticle-catalyzed chemiluminescence and its applications in detection of thiols and guanidine
| Autor: | Yanjun Zhao, Ying Wang, Meiling Wang, Aiping Fan, Lu Han |
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| Rok vydání: | 2018 |
| Předmět: |
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Metal Nanoparticles chemical and pharmacologic phenomena 02 engineering and technology 01 natural sciences Horseradish peroxidase Catalysis Analytical Chemistry Luminol law.invention chemistry.chemical_compound Limit of Detection Superoxides law Humans Sulfhydryl Compounds Guanidine Horseradish Peroxidase Chemiluminescence Iodophenol Singlet Oxygen biology Iodobenzenes Singlet oxygen 010401 analytical chemistry Hydrogen Peroxide 021001 nanoscience & nanotechnology 0104 chemical sciences Solutions chemistry Colloidal gold Luminescent Measurements biology.protein Gold 0210 nano-technology Nuclear chemistry |
| Zdroj: | Talanta. 182:523-528 |
| ISSN: | 0039-9140 |
| DOI: | 10.1016/j.talanta.2018.01.093 |
| Popis: | In the present study, the effects of nine compounds on the luminol-O2 chemiluminescence (CL) reaction catalyzed by gold nanoparticles (Au NPs) were investigated. p-Iodophenol (PIP), known as a traditional enhancer in horseradish peroxidase (HRP)-catalyzed luminol-H2O2 CL reaction, exhibited the highest enhancement effect on the luminol-O2-Au NPs CL reaction. The addition of PIP at a final concentration of 1.25 mM to luminol-O2-Au NPs CL system enhanced the CL signal almost 30-fold. Interestingly, the enhanced CL reaction exhibited a slow and intense CL signal which is different from the CL profile of luminol-H2O2-Au NPs CL system reported in previously. The experimental conditions of the PIP enhanced luminol-O2-Au NPs CL system were investigated systematically in the present study. And the mechanism studies showed that superoxide anion (O2•-) and singlet oxygen (1O2) generated from dissolved oxygen played an important role during the CL reaction. Furthermore, the effects of some organic compounds on the enhanced CL system were investigated. The results showed that compounds containing -SH and guanidine group can inhibit the signal of the enhanced CL reaction indicating the applicability of the proposed CL reaction for the detection of such compounds. |
| Databáze: | OpenAIRE |
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