Pulmonary alveolar microlithiasis: Blizzard of lung
| Autor: | Siddharth Yadav, Rohit Kumar, Richa Mittal, Shibdas Chakrabarti, Juvva Kishan Srikanth, Ravi Chandak |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Pulmonary and Respiratory Medicine
Lung Diseases Pediatrics medicine.medical_specialty Disease Asymptomatic 03 medical and health sciences 0302 clinical medicine Pathognomonic Snow pulmonary calcifications medicine Humans 030212 general & internal medicine Child Lung microliths Aged business.industry Genetic Diseases Inborn Calcinosis medicine.disease medicine.anatomical_structure 030228 respiratory system Pulmonary alveolar microlithiasis Radiological weapon Medicine Female Presentation (obstetrics) medicine.symptom Cardiology and Cardiovascular Medicine business Rare disease |
| Zdroj: | Monaldi Archives for Chest Disease (2021) |
| Popis: | Pulmonary alveolar microlithiasis (PAM) is a rare inherited disorder in which patients present with either nonspecific signs and symptoms or are asymptomatic. Clinical-radiological dissociation is a commonly seen feature of the disease. Majority of cases are diagnosed in second and third decade of life, although presentation in paediatric and elderly population is also reported. Pathognomonic radiological findings, with normal calcium and phosphate levels can confirm the diagnosis without the need of further investigations in large number of cases. A high index of suspicion and knowledge of the disease is of paramount importance as it has a wide range of presentation and variable course thus posing a diagnostic challenge. We present two cases of this rare disease in elderly females with distinct presentations although with similar and characteristic radiological findings along with a brief review of literature of the disease. |
| Databáze: | OpenAIRE |
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