Cardiovascular outcomes in patients with intraventricular conduction blocks: A sixteen-year follow-up in a state-wide database
Autor: | John S Pantazopoulos, William J. Kostis, John B. Kostis, Alice David, Nora M. Cosgrove |
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Rok vydání: | 2016 |
Předmět: |
Male
medicine.medical_specialty lcsh:Diseases of the circulatory (Cardiovascular) system Intraventricular blocks Bundle-Branch Block Myocardial Ischemia Comorbidity Coronary Artery Disease 030204 cardiovascular system & hematology Cardiovascular System 03 medical and health sciences Ventricular Dysfunction Left 0302 clinical medicine Internal medicine Medicine Humans In patient 030212 general & internal medicine Mortality Mitral regurgitation Aged Aged 80 and over Heart Failure Medicine(all) business.industry Left bundle branch block Absolute risk reduction Atrial fibrillation Right bundle branch block Intraventricular conduction Middle Aged medicine.disease lcsh:RC666-701 Cardiovascular Diseases Anesthesia Heart failure Cardiology Cardiovascular death Female Cardiology and Cardiovascular Medicine business Cardiovascular outcomes Follow-Up Studies |
Zdroj: | Hellenic Journal of Cardiology, Vol 58, Iss 3, Pp 194-201 (2017) |
ISSN: | 1109-9666 |
DOI: | 10.1016/j.hjc.2016.11.034 |
Popis: | Background: To assess the adverse clinical effects of left anterior hemiblock alone or in combination with right bundle branch block and of complete left bundle branch block in comparison with isolated right bundle branch block and the relationship of these effects with altered mechanoelectric factors resulting in left ventricular dysfunction. Methods: In a 16-year follow-up study using a statewide database, we studied the occurrence of mortal and morbid cardiovascular (CV) events among patients without apparent ischemic heart disease who had left anterior hemiblock (LAHB, n=4273, right bundle branch block (RBBB) with LAHB (BFBB, n=1857) and left bundle branch block (LBBB, n=9484 compared to isolated RBBB (n=25288). Results: After adjustment for demographics, co-morbidities and insurance, LAHB was associated with a significant excess risk of all-cause death (HR 1.134, 95% CI 1.061-1.213, p=0.0002) and CV death (HR 1.329, 95% CI 1.174-1.501, p |
Databáze: | OpenAIRE |
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