Cardiovascular outcomes in patients with intraventricular conduction blocks: A sixteen-year follow-up in a state-wide database

Autor: John S Pantazopoulos, William J. Kostis, John B. Kostis, Alice David, Nora M. Cosgrove
Rok vydání: 2016
Předmět:
Male
medicine.medical_specialty
lcsh:Diseases of the circulatory (Cardiovascular) system
Intraventricular blocks
Bundle-Branch Block
Myocardial Ischemia
Comorbidity
Coronary Artery Disease
030204 cardiovascular system & hematology
Cardiovascular System
03 medical and health sciences
Ventricular Dysfunction
Left

0302 clinical medicine
Internal medicine
Medicine
Humans
In patient
030212 general & internal medicine
Mortality
Mitral regurgitation
Aged
Aged
80 and over

Heart Failure
Medicine(all)
business.industry
Left bundle branch block
Absolute risk reduction
Atrial fibrillation
Right bundle branch block
Intraventricular conduction
Middle Aged
medicine.disease
lcsh:RC666-701
Cardiovascular Diseases
Anesthesia
Heart failure
Cardiology
Cardiovascular death
Female
Cardiology and Cardiovascular Medicine
business
Cardiovascular outcomes
Follow-Up Studies
Zdroj: Hellenic Journal of Cardiology, Vol 58, Iss 3, Pp 194-201 (2017)
ISSN: 1109-9666
DOI: 10.1016/j.hjc.2016.11.034
Popis: Background: To assess the adverse clinical effects of left anterior hemiblock alone or in combination with right bundle branch block and of complete left bundle branch block in comparison with isolated right bundle branch block and the relationship of these effects with altered mechanoelectric factors resulting in left ventricular dysfunction. Methods: In a 16-year follow-up study using a statewide database, we studied the occurrence of mortal and morbid cardiovascular (CV) events among patients without apparent ischemic heart disease who had left anterior hemiblock (LAHB, n=4273, right bundle branch block (RBBB) with LAHB (BFBB, n=1857) and left bundle branch block (LBBB, n=9484 compared to isolated RBBB (n=25288). Results: After adjustment for demographics, co-morbidities and insurance, LAHB was associated with a significant excess risk of all-cause death (HR 1.134, 95% CI 1.061-1.213, p=0.0002) and CV death (HR 1.329, 95% CI 1.174-1.501, p
Databáze: OpenAIRE