Amniotic fluid alpha-fetoprotein subfractions in fetal Trisomy 21 affected pregnancies

Autor: Stephen R. Jones, Louise Gillan, Stuart E. Evans
Rok vydání: 1988
Předmět:
Zdroj: BJOG: An International Journal of Obstetrics and Gynaecology. 95:327-329
ISSN: 1471-0528
1470-0328
DOI: 10.1111/j.1471-0528.1988.tb06600.x
Popis: Summary. The percentage contribution to the total AFP concentration in amniotic fluid from the yolk sac derived AFP was measured at 15–17 weeks gestation in 15 pregnancies affected by fetal Trisomy 21 and compared with that in 75 pregnancies with a normal outcome. The yolk sac form of AFP was reduced in parallel to the total AFP and differentiation of the subtraction from the yolk sac would offer no increase in diagnostic efficiency.
Databáze: OpenAIRE