Chiral Imidazolidin-4-one with catalytic amount of Dicationic ionic liquid act as a recoverable and reusable Organocatalyst for asymmetric Diels-Alder reaction
| Autor: | Mohd Jubair Aalam, Deepa, Surendra Singh, Geeta Devi Yadav, Dhan Raj Meena, Pooja Chaudhary |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Pharmacology
Cyclopentadiene 010405 organic chemistry Organic Chemistry Substrate (chemistry) 010402 general chemistry 01 natural sciences Catalysis 0104 chemical sciences Analytical Chemistry chemistry.chemical_compound chemistry Drug Discovery Ionic liquid Trifluoroacetic acid Organic chemistry Crotonaldehyde Spectroscopy Diels–Alder reaction |
| Zdroj: | ChiralityREFERENCES. 32(1) |
| ISSN: | 1520-636X |
| Popis: | Imidazolidin-4-one is used as a recoverable organocatalyst for the asymmetric Diels-Alder reaction in the presence of catalytic amount of dicationic ionic liquid and trifluoroacetic acid as a co-catalyst. The Diels-Alder reaction between model substrate cyclopentadiene and crotonaldehyde gave the product in 95% conversion and 87% ee of the endo-product. The catalyst was shown better reusability when the 20 mol% of dicationic ionic liquid was used and catalyst was reused upto 5 cycles, conversion remains upto 3 recycles but ee of endo-9 was slightly droped. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text