Swept Source Optical Coherence Tomography Assessment of Bursa Premacularis in Healthy Eyes
Autor: | Marta Di Nicola, Luca Di Antonio, Lisa Toto, Giuseppe Di Martino, Rodolfo Mastropasqua, Daniele Guarini, Katia Clemente, Luca Cerino, Carla Iafigliola, Rossella D'Aloisio, Paolo Carpineto, Elisabetta Sciarroni |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
0301 basic medicine
Adult Male Fovea Centralis Article Subject Intraclass correlation Population General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Optical coherence tomography medicine Humans education education.field_of_study General Immunology and Microbiology medicine.diagnostic_test business.industry Reproducibility of Results General Medicine Vitreous Body 030104 developmental biology Cross-Sectional Studies 030221 ophthalmology & optometry Medicine Female business Nuclear medicine Tomography Optical Coherence Research Article |
Zdroj: | BioMed Research International BioMed Research International, Vol 2020 (2020) |
ISSN: | 2314-6141 2314-6133 |
Popis: | Purpose. To describe the reliability and the limits of bursa premacularis (BPM) evaluation using a swept source optical coherence tomography (SS-OCT) device with enface and 16 mm-high definition (HD) longitudinal scans. Methods. 60 eyes of 60 subjects were enrolled and imaged with SS-OCT system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). BPM area was measured using enface scans imported to ImageJ. HD horizontal and vertical longitudinal scans centered at the fovea were used to detect width (W) and central thickness (CT) of BPM at baseline (T0) and after 30 minutes (T30) performed by two different observers. An enhanced vitreous visualization software provided by the manufacturer of the device was used to highlight vitreous structures. Results. BPM was identifiable in 100% of eyes using both horizontal and vertical longitudinal scans. On horizontal scan, BPM was not entirely measurable in 21.7% and in 18.3% of cases at T0 and T30, respectively. On vertical scan, BPM was not entirely measurable in 75.0% and in 81.7% at T0 and T30, respectively. No statistically significant differences were found between the two different time measurements with an intraclass correlation coefficient above 70%. Median BPM area was 26.9 (Q1-Q3: 19.5-40.5) mm2. In en face imaging, the most frequent BPM shape was the boat one. Conclusion. SS-OCT is a reliable tool for a detailed quantification and mapping of BPM, and it is able to add useful details about the morphological BPM features in youth population. However, the enhanced visualization of the vitreous structures is still a challenge, also with the most forefront devices. |
Databáze: | OpenAIRE |
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