Antibacterial and Phytochemical Study of Iraqi Salvia officinalis Leave Extracts
| Autor: | Alaadin M. Naqishbandi, Lana Y. Muttalib |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
food.ingredient
Gram-positive bacteria Saponin medicine.disease_cause Analytical Chemistry Microbiology chemistry.chemical_compound food Pharmacy and materia medica medicine Pharmacology (medical) Thujone General Pharmacology Toxicology and Pharmaceutics chemistry.chemical_classification Traditional medicine biology Chemistry Salvia officinalis biology.organism_classification food.food RS1-441 Phytochemical Staphylococcus aureus Herb Salvia officinalis Antibacterial TLC Thujone Bacteria |
| Zdroj: | Iraqi Journal of Pharmaceutical Sciences, Vol 21, Iss 1 (2017) |
| ISSN: | 1683-3597 2521-3512 |
| Popis: | Sage (Salvia officinalis), belong to Labiatae family is indigenous to Iraq and other Mediterranean areas but now cultivated world- wide, principally for its use as culinary herb. In the present study preliminary screening for the important phytochemical natural product groups indicated the presence of flavonoid, saponin, hyrolysable and condensed tannin groups. The antibacterial activity of two concentrations 10 mg/ml and 100 mg/ml of chloroform and hydroalcoholic extracts from Salvia officinalis leaves was evaluated against four strains of gram negative bacteria (Escherichia coli, Pseudomonas arigenossa, Klebsiella pneumonia, and Proteus spp) and two strains of gram positive bacteria (Staphylococcus aureus, Bacillus cerus) using agar well diffusion method. Chloroform extract 100mg/ml was found active against two types of bacteria, Staphylococcus aureus with MIC of 90 mg/ml and Proteus spp with MIC of 80 mg/ml. Bioassay guided separation using TLC led to the separation of 6 constituents from the active extract, one of them was identified as thujone. Key words: Salvia officinalis, Antibacterial, TLC, Thujone. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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