Impact of Atopic Dermatitis Lesion Location on Quality of Life in Adult Patients in a Real-world Study
Autor: | Andreas Wollenberg, James Piercy, Peter A. Lio, Amy M. DeLozier, Maria Jose Rueda, Carle Paul, Jorge A. Ross Terres, Gary Milligan, Jacob P. Thyssen, Peter Anderson, Evangeline Pierce, Jonathan I. Silverberg |
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Rok vydání: | 2020 |
Předmět: |
Adult
Male 0301 basic medicine medicine.medical_specialty Esthetics Severity of Illness Index Dermatitis Atopic Lesion Young Adult 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Quality of life Surveys and Questionnaires Severity of illness medicine Humans Young adult Depression (differential diagnoses) Skin Body surface area business.industry General Medicine Atopic dermatitis Dermatology Life Quality Index Middle Aged Hand medicine.disease Dermatology humanities 030104 developmental biology Lower Extremity Quality of Life Female medicine.symptom business Head Neck |
Zdroj: | Journal of Drugs in Dermatology. 19:943-948 |
ISSN: | 1545-9616 |
Popis: | Background Atopic dermatitis (AD) has a negative impact on patientsr quality of life (QoL). Objective To report the impact of specific AD lesion locations on QoL in adult patients with AD using real-world data. Methods The Adelphi US Disease Specific Programme was conducted between JanuarynApril 2018. Physicians documented patient demographics/characteristics, AD lesion locations, and body surface area; patients completed questionnaires reporting the impact of lesion locations on QoL. Results AD severity was moderate in 51.6% of patients and severe in 6.0%. Lesions were commonly identified in more than one location. All AD lesion locations impacted QoL. Visible areas were most bothersome, including head/neck (68%), hands/fingers (58%), front (30%), upper extremities (22%), and lower extremities (16%), with statistically significant associations for a number of Dermatology Life Quality Index (DLQI) items. Itch, soreness, pain, and stinging are also associated with a number of body areas but in particular with those that are most visible/accessible. Lesions on the head/neck and hands/fingers (58%) demonstrated an increased impact on the anxiety and depression dimension of the EuroQol 5-Dimension tool. Conclusions In patients with AD, quality of life was most affected in patients with lesions in visible areas, including head/neck, hands/fingers, and upper extremities, with statistically significant associations for a number of DLQI domains. Physicians should be aware of the burden of AD lesions on QoL and consider having conversations with patients to better understand the impact of these lesions. Prior presentation: 28th Annual European Academy of Dermatology and Venereology Congress; 9n13 October 2019, Madrid, Spain. Poster number P0233.J Drugs Dermatol. 2020;19(10): 943-948. doi:10.36849/JDD.2020.5422. |
Databáze: | OpenAIRE |
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