Regulation of intestinal alkaline phosphatase by dietary phosphate
Autor: | L. W. McCuaig, I. Motzok |
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Rok vydání: | 1972 |
Předmět: |
medicine.medical_specialty
Time Factors Intestinal alkaline phosphatase Physiology Phosphates chemistry.chemical_compound Inorganic phosphate Physiology (medical) Internal medicine medicine Pi Animals Intestinal Mucosa Pharmacology chemistry.chemical_classification Starvation Cell Nucleus biology Age Factors Phosphorus General Medicine Phosphate Alkaline Phosphatase Enzyme assay Diet Intestines Endocrinology Enzyme Biochemistry chemistry biology.protein Alkaline phosphatase Female medicine.symptom Chickens |
Zdroj: | Canadian journal of physiology and pharmacology. 50(12) |
ISSN: | 0008-4212 |
Popis: | Day-old chicks were fed practical rations containing varying levels of inorganic phosphate (Pi) in an attempt to study the regulation of intestinal alkaline phosphatase by phosphate. Low dietary Pi (0.16%) increased the enzyme activity by 50% compared to adequate Pi (0.48%). The enzyme activities were significantly reversed 8 days after reversing the diets. In another experiment chicks were fed 0.16 or 0.80%) Pi for 4 weeks and killed when full-fed, or after 3 days' starvation. In the full-fed birds low dietary Pi reduced the intestinal nuclear Pi and doubled the intestinal enzyme activity. Nuclear Pi was found to be inversely correlated with alkaline phosphatase in the fed animals. No such effects were found in the starved birds. |
Databáze: | OpenAIRE |
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