Evaluation of chemical composition and antiedematogenic activity of the essential oil of Hyptis martiusii Benth
| Autor: | Cícera Datiane Morais de Oliveira, Cinara Soares Vidal, Andreza G.R. Barbosa, Rogério de Aquino Saraiva, Hericka Bruna Figueiredo Galvao, Luiz J. Lacerda-Neto, Irwin Rose Alencar de Menezes, José Galberto Martins da Costa, Henrique Douglas Melo Coutinho |
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| Rok vydání: | 2015 |
| Předmět: |
Thromboxane
Pharmacology 01 natural sciences Essential oil law.invention 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine law Croton oil Medicinal plants Antiedematogenic activity lcsh:QH301-705.5 Antiinflammatory effect Natural products biology Agricultural and Biological Sciences(all) biology.organism_classification Antimicrobial 0104 chemical sciences Bioavailability Carrageenan 010404 medicinal & biomolecular chemistry 1 8 cineole chemistry lcsh:Biology (General) 030220 oncology & carcinogenesis Hyptis martiusii Original Article Lamiaceae General Agricultural and Biological Sciences |
| Zdroj: | Saudi Journal of Biological Sciences, Vol 24, Iss 2, Pp 355-361 (2017) |
| ISSN: | 1319-562X |
| DOI: | 10.1016/j.sjbs.2015.10.004 |
| Popis: | Evaluations of the therapeutic potential of medicinal plants and their components have been the subject of many studies. Furthermore, the biological activities of various plant species have been reported in various pieces of literature. Hyptis martiusii Benth (Lamiaceae), popularly known as “mad balm” is commonly found in the North, Southeast, and Northeast of Brazil. Its leaves are used ethnobiologically as antiulcerogenic, antimicrobial, antitumor and as insecticide. This study aimed to analyze the chemical composition of the essential oil of H. martiusii Benth (OEHM) by GC/MS as well as its possible topical activity as an antiedematogenic. This is verified by the models of ear edema induced by single (acute edema) and multiple (chronic edema) applications of croton oil topically, and systemically verified through the model of paw edema induced by carrageenan 1%. Doses of 50, 75 and 100mg/kg OEHM were used in all tests. Chemical analysis of the oil revealed the 1,8-cineole (34.58%) and δ-carene (21:58%) as major components present in the essential oil. On the model of ear edema, acute and chronic OEHM in all the tested doses showed no significant antiedematogenic activity (p |
| Databáze: | OpenAIRE |
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