Variability associated with interpreting drugs within forensic hair analysis: A three‐stage interpretation
| Autor: | Agatha Grela, Lata Gautam, Christopher Davies, Joanne Morrissey |
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| Rok vydání: | 2020 |
| Předmět: |
Drug
media_common.quotation_subject Interpersonal communication 010501 environmental sciences Toxicology 01 natural sciences Chemistry Techniques Analytical Forensic Toxicology 03 medical and health sciences Drug facilitated sexual assault False positive paradox Humans 030304 developmental biology 0105 earth and related environmental sciences media_common 0303 health sciences Three stage Interpretation (philosophy) Hair analysis Forensic Medicine Substance Abuse Detection Pharmaceutical Preparations Data Interpretation Statistical Forensic-science Drug analysis Psychology Chromatography Liquid Hair Clinical psychology |
| Zdroj: | Journal of Applied Toxicology. 40:868-888 |
| ISSN: | 1099-1263 0260-437X |
| Popis: | Hair analysis is capable of determining both an individual's long-term drug history and a single exposure to a drug, which can be particularly important for corroborating incidents of drug-facilitated crimes. As a source of forensic evidence that may be used in a court of law, it must be credible, impartial and reliable, yet the pathways of drug and metabolite entry into hair are still uncertain. Many variables may influence drug analysis results, most of which are outside of the control of an analyst. An individual's pharmacokinetic and metabolic responses, hair growth rates, drug incorporation routes, axial migration, ethnicity, age and gender, for example, all display interpersonal variability. At present there is little standardization of the analytical processes involved with hair analysis. Both false positives and negative results for drugs are frequently encountered, regardless of whether a person has consumed a drug or not. In this regard, we have categorized these variables and proposed a three-stage analytical approach to facilitate forensic toxicologists, hair analysis experts, judiciaries and service users in the analytical and interpretation process. [Abstract copyright: © 2020 John Wiley & Sons, Ltd.] |
| Databáze: | OpenAIRE |
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