Effectiveness of theophylline to increase cyclic AMP levels and force of contraction in electrically paced guinea-pig auricles. Comparison with isoprenaline, calcium and ouabain
| Autor: | Barbara Schmelzle, Claudia Dönges, Martin Heitmann, Harald Jungbluth, Thomas Meinertz, Hasso Scholz |
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| Rok vydání: | 1977 |
| Předmět: |
Male
medicine.medical_specialty Time Factors Contraction (grammar) Guinea Pigs chemistry.chemical_element In Vitro Techniques Calcium Ouabain Guinea pig Theophylline Internal medicine Isoprenaline Cyclic AMP medicine Animals Pharmacology Chemistry Myocardium Cardiac Pacing Artificial Isoproterenol General Medicine Reserpine Myocardial Contraction Propranolol C++ AMP Endocrinology Female medicine.drug |
| Zdroj: | Naunyn-Schmiedeberg's Archives of Pharmacology. 301:87-97 |
| ISSN: | 1432-1912 0028-1298 |
| Popis: | The effects of theophylline (3×10−5 M–5×10−3 M), isoprenaline (10−6 M), excess calcium (7.2 mM) and ouabain (3×10−7 M) on force of contraction and c-AMP content were studied in electrically driven (frequency 3 Hz) left auricles isolated from guinea pigs pretreated with reserpine. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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