Plasma prolactin/oestradiol ratio at 38 weeks gestation predicts the duration of lactational amenorrhoea

Autor: Silvia Catalán, Verónica Valdés, Andrés Poblete, María Serón-Ferré, Cristián Belmar, Carmen Campino, Alonso Rioseco, Claudia Uribe Torres, Edda Pugin
Rok vydání: 2001
Předmět:
Zdroj: Human Reproduction. 16:2540-2545
ISSN: 1460-2350
0268-1161
DOI: 10.1093/humrep/16.12.2540
Popis: BACKGROUND: Fully breastfeeding women experience an amenorrhoea of variable duration. Our aim was to identify in pregnancy, endocrine markers that could predict the duration of subsequent lactational amenorrhoea. METHODS: We studied 17 healthy women at 34 and 38 weeks gestation, and 1 and 3 months post-partum. The women fully breastfed until 6 months post-partum. During pregnancy, prolactin (PRL), oestrogens (total oestradiol, unconjugated oestrone, unconjugated oestriol), sex hormone binding globulin (SHBG), dehydroepiandrosterone sulphate (DHEA-S), progesterone and placental lactogen, and during post-partum PRL, oestrogens and SHBG, were measured. Free oestradiol in pregnancy and post-partum was calculated. RESULTS: Ten women experienced long (>6 months) and seven experienced short (
Databáze: OpenAIRE