Effects of echo time on diffusion quantification of brain white matter at 1.5T and 3.0T

Autor: Fan Zhang, Xiang Ying Du, Chun Shui Yu, Heng Jiang, Kun Cheng Li, Wen Qin, Yu Xia Yan
Rok vydání: 2009
Předmět:
Zdroj: Magnetic Resonance in Medicine. 61:755-760
ISSN: 1522-2594
0740-3194
DOI: 10.1002/mrm.21920
Popis: The aim was to investigate the effects of echo time (TE) on diffusion quantification of brain white matter. Seven rhesus monkeys (all males; age, 4 – 6 years; weight, 5–7 kg) underwent diffusion tensor imaging (DTI) with a series of TEs in 1.5T and 3.0T MR scanners. The mean diffusivity (MD), fractional anisotropy (FA), primary (1), and transverse eigenvalues (23) were measured in a region of interest at the bilateral internal capsule. Pearson correlation showed that the FA and 1 increased and 23 decreased with TE both at 1.5T and 3.0T except for the MD. Repeated measurement analysis of variance (ANOVA) also showed significantly higher FA and lower MD and 23 at 3.0T than those at 1.5T (P < 0.01), but no statistical differences were found in 1 between these two field strengths (P 0.709). These findings implied that TE and field strength might influence diffusion quantification in brain white matter. Magn Reson Med 61:755–760, 2009. © 2009 Wiley-Liss, Inc.
Databáze: OpenAIRE