Lung ultrasound score to monitor COVID-19 pneumonia progression in patients with ARDS
| Autor: | Dargent, Auguste, Chatelain, Emeric, Kreitmann, Louis, Quenot, Jean-Pierre, Cour, Martin, Argaud, Laurent, COVID-LUS study group |
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| Přispěvatelé: | Service de Médecine Intensive et Réanimation [Lyon] (MIR), Hôpital Edouard Herriot [CHU - HCL], Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon, Service de Réanimation Médicale (CHU de Dijon), Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Excellence : Lipoprotéines et Santé : prévention et Traitement des maladies Inflammatoires et du Cancer (LabEx LipSTIC), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut Gustave Roussy (IGR)-Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)-Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon)-Université de Bourgogne (UB)-Centre Hospitalier Universitaire de Dijon - Hôpital François Mitterrand (CHU Dijon)-Centre Régional de Lutte contre le cancer Georges-François Leclerc [Dijon] (UNICANCER/CRLCC-CGFL), UNICANCER-UNICANCER-Institut National de la Santé et de la Recherche Médicale (INSERM)-Fédération Francophone de la Cancérologie Digestive, FFCD-Université de Montpellier (UM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Etablissement français du sang [Bourgogne-Franche-Comté] (EFS [Bourgogne-Franche-Comté])-Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), COVID-LUS study group, Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Bodescot, Myriam |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
ARDS Pulmonology medicine.medical_treatment [SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract law.invention Hypoxemia Diagnostic Radiology 0302 clinical medicine law [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases Ultrasound Imaging Medicine and Health Sciences Intubation 030212 general & internal medicine Lung Materials Optical Properties Tomography Ultrasonography [SDV.MP.VIR] Life Sciences [q-bio]/Microbiology and Parasitology/Virology Respiratory Distress Syndrome Multidisciplinary Radiology and Imaging Pneumonia Ventilator-Associated Middle Aged Thorax Intensive care unit Hospitals 3. Good health Intensive Care Units medicine.anatomical_structure Physical Sciences [SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology Disease Progression Pleurae [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases Medicine Female France medicine.symptom Anatomy Coronavirus Infections Research Article Opacity medicine.medical_specialty Imaging Techniques Amorphous Solids Science Pneumonia Viral Materials Science Material Properties Research and Analysis Methods 03 medical and health sciences Betacoronavirus Diagnostic Medicine Intensive care medicine Humans Intensive care medicine Pandemics Mechanical ventilation business.industry SARS-CoV-2 COVID-19 Biology and Life Sciences Pneumonia medicine.disease respiratory tract diseases Health Care Glass Ultrasound imaging Intensive care units 030228 respiratory system Health Care Facilities [SDV.MHEP.PSR] Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract business Tomography X-Ray Computed |
| Zdroj: | PLOS ONE, 15(7):e0236312 PLoS ONE PLoS ONE, Public Library of Science, 2020, 15 (7), pp.e0236312. ⟨10.1371/journal.pone.0236312⟩ PLoS ONE, Vol 15, Iss 7, p e0236312 (2020) PLoS ONE, 2020, 15 (7), pp.e0236312. ⟨10.1371/journal.pone.0236312⟩ |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0236312⟩ |
| Popis: | International audience; COVID-19 pneumonia typically begins with subpleural ground glass opacities with progressive extension on computerized tomography studies. Lung ultrasound is well suited to this interstitial, subpleural involvement, and it is now broadly used in intensive care units (ICUs). The extension and severity of lung infiltrates can be described numerically with a reproducible and validated lung ultrasound score (LUSS). We hypothesized that LUSS might be useful as a tool to non-invasively monitor the evolution of COVID-19 pneumonia at the bedside. LUSS monitoring was rapidly implemented in the management of our COVID-19 patients with RT-PCR-documented COVID-19. The LUSS was evaluated repeatedly at the bedside. We present a graphic description of the course of LUSS during COVID-19 in 10 consecutive patients admitted in our intensive care unit with moderate to severe ARDS between March 15 and 30th. LUSS appeared to be closely related to the disease progression. In successfully extubated patients, LUSS decreased and was lower than at the time of intubation. LUSS increased inexorably in a patient who died from refractory hypoxemia. LUSS helped with the diagnosis of ventilator-associated pneumonia (VAP), showing an increased score and the presence of new lung consolidations in all 5 patients with VAPs. There was also a good agreement between CT-scans and LUSS as for the presence of lung consolidations. In conclusion, our early experience suggests that LUSS monitoring accurately reflect disease progression and indicates potential usefulness for the management of COVID-19 patients with ARDS. It might help with early VAP diagnosis, mechanical ventilation weaning management, and potentially reduce the need for X-ray and CT exams. LUSS evaluation is easy to use and readily available in ICUs throughout the world, and might be a safe, cheap and simple tool to optimize critically ill COVID-19 patients care during the pandemic. |
| Databáze: | OpenAIRE |
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