Decreased serum vitamin D levels in early spontaneous pregnancy loss
| Autor: | Xue-Wen Yu, Bai Cm, Xinwen Zhang, Lingyun Hui, Hou W, Xiao-Ting Yan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Vitamin
Adult medicine.medical_specialty Medicine (miscellaneous) 030209 endocrinology & metabolism Gestational Age Gravidity vitamin D deficiency 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Blood serum Pregnancy Internal medicine Vitamin D and neurology medicine Odds Ratio Humans Vitamin D 25-Hydroxyvitamin D3 1-alpha-Hydroxylase 030219 obstetrics & reproductive medicine Nutrition and Dietetics business.industry Pregnancy Outcome Gestational age medicine.disease Vitamin D Deficiency Abortion Spontaneous Pregnancy Complications Parity Endocrinology Cross-Sectional Studies chemistry Case-Control Studies Gestation Calcifediol Original Article Female business |
| Zdroj: | European Journal of Clinical Nutrition |
| ISSN: | 1476-5640 0954-3007 |
| Popis: | Background/Objectives: Effects of vitamin D deficiency in pregnancy have been associated with some adverse pregnancy outcomes. The objective of this study was to analyze the relationship between vitamin D deficiency in childbearing aged women and pregnancy loss (PL) in the first trimester. Subjects/Methods: This is a cross-sectional study. Plasma was collected from 60 nulliparous women with singleton at 7–9 weeks of gestation (30 with viable gestation and 30 with PL) and 60 non-gravid childbearing aged women (30 with a successful pregnancy history, and 30 with one or more spontaneous first-trimester PL history). Quantitation of serum 25-hydroxyvitamin D (25(OH)D) and 25-hydroxyvitamin D-1 alpha hydroxylase (CYP27B1) was assayed. Results: By pregnancy/non-gravid, normal pregnant women had higher 25(OH)D (49.32 μg/l) and CYP27B1 (82.00 pg/ml) than PL women (34.49 μg/l and 37.87 pg/ml, both P |
| Databáze: | OpenAIRE |
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