Results of an independent dosimetry audit for scanned proton beam therapy facilities
| Autor: | Jörg Wulff, C. Gouldstone, Markus Stock, Ole Noerrevang, Benjamin Koska, A. Carlino, Hugo Palmans, Stefano Lorentini, Anne Vestergaard, Geert Bosmans, P. Trnkova, S. Vatnitsky, Marco Schwarz, Gloria Vilches Freixas |
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| Přispěvatelé: | Radiation Oncology |
| Rok vydání: | 2020 |
| Předmět: |
Ion beam
medicine.medical_treatment Medizin Biophysics Alanine dosimeters Audit Imaging phantom 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Proton Therapy Medicine Dosimetry Radiology Nuclear Medicine and imaging Radiation treatment planning Radiometry Proton therapy Radiological and Ultrasound Technology business.industry Phantoms Imaging End-to-end test Radiotherapy Planning Computer-Assisted Radiotherapy Dosage Dosimetry audit Radiation therapy Ionization chamber Protons Nuclear medicine business |
| Zdroj: | Zeitschrift fur Medizinische Physik, 31(2), 145-153. Urban und Fischer Verlag Jena Carlino, A, Palmans, H, Gouldstone, C, Trnkova, P, Noerrevang, O, Vestergaard, A, Freixas, G V, Bosmans, G, Lorentini, S, Schwarz, M, Koska, B, Wulff, J, Vatnitsky, S & Stock, M 2021, ' Results of an independent dosimetry audit for scanned proton beam therapy facilities ', Zeitschrift fur Medizinische Physik, vol. 31, no. 2, pp. 145-153 . https://doi.org/10.1016/j.zemedi.2021.01.003 |
| ISSN: | 1876-4436 0939-3889 |
| Popis: | Purpose An independent dosimetry audit based on end-to-end testing of the entire chain of radiation therapy delivery is highly recommended to ensure consistent treatments among proton therapy centers. This study presents an auditing methodology developed by the MedAustron Ion Beam Therapy Center (Austria) in collaboration with the National Physical Laboratory (UK) and audit results for five scanned proton beam therapy facilities in Europe. Methods The audit procedure used a homogeneous and an anthropomorphic head phantom. The phantoms were loaded either with an ionization chamber or with alanine pellets and radiochromic films. Homogeneously planned doses of 10 Gy were delivered to a box-like target volume in the homogeneous phantom and to two clinical scenarios with increasing complexity in the head phantom. Results For all tests the mean of the local differences of the absolute dose to water determined with the alanine pellets compared to the predicted dose from the treatment planning system installed at the audited institution was determined. The mean value taken over all tests performed was −0.1 ± 1.0%. The measurements carried out with the ionization chamber were consistent with the dose determined by the alanine pellets with a mean deviation of −0.5 ± 0.6%. Conclusion The developed dosimetry audit method was successfully applied at five proton centers including various “turn-key” Cyclotron solutions by IBA, Varian and Mevion. This independent audit with extension to other tumour sites and use of the correspondent anthropomorphic phantoms may be proposed as part of a credentialing procedure for future clinical trials in proton beam therapy. |
| Databáze: | OpenAIRE |
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