| Autor: |
Lindsay R Grant, Mary P E Slack, Christian Theilacker, Jelena Vojicic, Stephane Dion, Ralf-Rene Reinert, Luis Jodar, Bradford D Gessner |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. |
| ISSN: |
1537-6591 |
| Popis: |
Background The introduction and adoption of pneumococcal conjugate vaccines (PCVs) into pediatric national immunization programs (NIPs) has led to large decreases in invasive pneumococcal disease (IPD) incidence caused by vaccine serotypes. Despite these reductions, the global IPD burden in children remains significant. Methods We collected serotype-specific IPD data from surveillance systems or hospital networks of all 30 high-income countries that met inclusion criteria. Data sources included online databases, surveillance system reports, and peer-reviewed literature. Percentage of serotyped cases covered were calculated for all countries combined and by PCV type in the pediatric NIP. Results We identified 8012 serotyped IPD cases in children Conclusions Much of the remaining IPD burden is due to serotypes included in PCV15 and PCV20. The inclusion of these next generation PCVs into existing pediatric NIPs may further reduce the incidence of childhood IPD. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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