Anterior Spinal Arthrodesis With Structural Cortical Allografts and Instrumentation for Spine Tumor Surgery
| Autor: | Thomas F. DeLaney, Peter A. Chapman, Kai-Uwe Lewandrowski, Frank X. Pedlow, Francis J. Hornicek, Andrew C. Hecht |
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| Rok vydání: | 2004 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Adolescent medicine.medical_treatment Arthrodesis Chondrosarcoma Metastasis Central nervous system disease Postoperative Complications Chordoma medicine Deformity Humans Transplantation Homologous Orthopedics and Sports Medicine Intraoperative Complications Rachis Aged Retrospective Studies Osteosarcoma Bone Transplantation Braces Spinal Neoplasms business.industry Carcinoma Middle Aged medicine.disease Combined Modality Therapy Survival Analysis Internal Fixators Neoadjuvant Therapy Surgery Radiation therapy Spinal Fusion Treatment Outcome medicine.anatomical_structure Chemotherapy Adjuvant Female Radiotherapy Adjuvant Cortical bone Tumor surgery Neurology (clinical) Neoplasm Recurrence Local medicine.symptom business |
| Zdroj: | Spine. 29:1150-1158 |
| ISSN: | 0362-2436 |
| DOI: | 10.1097/00007632-200405150-00019 |
| Popis: | STUDY DESIGN The authors report on anterior vertebral reconstruction following tumor resection with use of fresh-frozen, cortical, long-segment allografts prepared from diaphyseal sections of long bones. A retrospective analysis of clinical outcomes is presented. OBJECTIVE To analyze the results following the use of cortical allografts in the treatment of spine tumors. SUMMARY OF BACKGROUND DATA Metastatic disease and primary spinal bone tumors may result in progressive vertebral collapse, instability, deformity, pain, and neurologic deficit. Controversy as to the appropriate type of anterior reconstruction and/or graft material persists. METHODS From 1995 until 2001, 30 patients with primary spinal bone tumors or metastases to the spine were treated by anterior vertebral reconstruction with fresh-frozen cortical bone allografts. Grafts were used in combination with anterior and posterior instrumentation. RESULTS The median survival was 14 months. Ninety-three percent of all allografts were radiographically incorporated as early as 6 months after surgery in spite of adjuvant chemotherapy and radiation therapy. Fourteen patients (46%) had intraoperative or postoperative complications. Two patients underwent revision surgery for local recurrence. There were no allograft infections, fractures, or collapse. CONCLUSION Anterior column reconstruction with structural cortical allografts proved to be a reliable technique in patients with spine tumors. Postoperative complications can often be successfully managed. |
| Databáze: | OpenAIRE |
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