Meningovascular Syphilis Presenting as a Brain Mass in an Immunocompetent Male
| Autor: | Grace A Maldarelli, Joshua A. Lieberman, Matthew S. Simon, Khanh Pham, Alex Trzebucki, Babacar Cisse, David J. Pisapia, Lee Gottesdiener, Elliot DeHaan |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Pathology
medicine.medical_specialty Treponema medicine.diagnostic_test biology business.industry Brain biopsy Brain Mass Meningovascular syphilis Disease biology.organism_classification medicine.disease AcademicSubjects/MED00290 PCR Infectious Diseases incipient gumma Oncology Parenchyma Gumma Medicine Novel ID Cases Syphilis meningovascular syphilis business |
| Zdroj: | Open Forum Infectious Diseases |
| ISSN: | 2328-8957 |
| DOI: | 10.1093/ofid/ofab455 |
| Popis: | We present a case of a human immunodeficiency virus–negative man with syphilitic meningovascular disease with subjacent involvement of brain parenchyma leading to a mass-forming inflammatory lesion that was pathologically distinct from a typical gumma. Syphilis was diagnosed after tissue obtained from a brain biopsy demonstrated spirochetes consistent with Treponema pallidum and confirmed by 16S ribosomal RNA sequencing. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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