Effect of thyroid hormone on the pathways of glucose oxidation in the intact rat
| Autor: | Elizabeth Ford, Ernest Beutler, James L. Spratt, Thomas Necheles |
|---|---|
| Rok vydání: | 1962 |
| Předmět: |
endocrine system
medicine.medical_specialty Thyroid Hormones endocrine system diseases Chemistry Thyroid Thyroid Gland Carbohydrate metabolism Pentose phosphate pathway General Biochemistry Genetics and Molecular Biology Hormones Rats medicine.anatomical_structure Endocrinology Glucose Thyroid hormones Internal medicine medicine Animals Carbohydrate Metabolism Euthyroid Oxidation-Reduction Hormone |
| Zdroj: | Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 109 |
| ISSN: | 0037-9727 |
| Popis: | SummaryThese experiments suggest that whereas in the hyperthyroid animal the rate of oxidation of both the C-1 and C-6 carbon of glucose are increased to approximately the same extent, removal of the thyroid hormones leads to a proportionally greater reduction in rate of oxidation of the C-1 carbon. Thus it appears probable that in the euthyroid animal the rate of oxidation of the carbon-1 of glucose (presumably reflecting rate of oxidation via the phosphogluconate pathway) is under the influence of the thyroid gland. |
| Databáze: | OpenAIRE |
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