[The value of cerebral angiography using iodide substances in the diagnosis of glioblastoma]

Autor: Montrieul B, Philippides D, Steimle R
Rok vydání: 1953
Předmět:
Zdroj: Acta neurochirurgica. 3(3)
ISSN: 0001-6268
Popis: 85 cases of histologically confirmed glioblastoma multiforme were studied with angiography using the iodide substances Umbradil and Diodone, first at 50% and later at 35%. In the first group of 50 angiograms only lateral and frontal views were taken (arteriocapillary period). Each exposure was taken with 8 or 10 cc. of contrast substance. This series of 50 arteriograms, taken with Umbradil and Diodone, showed classical aspects of the tumor in not more than 20% of the cases while evidences of vascularization characteristic of glioblastoma appeared in 50 to 70% of the arteriograms taken under the same conditions using Thorotrast. The second group of 35 cases was studied using serial angiograms with 35% Diodone (average quantity injected: 15 to 18 cc.); 48% of these angiograms showed aspects of pathological intra-tumor vascularization. Several factors, i. e., the intensity of contrast, the viscosity, and the quantity of substance injected, must be taken into account to justify the varying proportions of positive films obtained with iodide substances compared to the results obtained with Thorotrast. In spite of the lower viscosity of Diodone, if a sufficient quantity of this substance is injected, the percentage of films showing characteristics of glioblastoma multiforme is almost equal to that obtained with Thorotrast. Moreover since the characteristics are evident particularly in the arterio-capillary period, the method of serial exposures does not add data of any considerable importance in this investigation.
Databáze: OpenAIRE
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