Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation

Autor:	Johannes Morstein, Taysir Bader, Ariana L. Cardillo, Julian Schackmann, Sudhat Ashok, James L. Hougland, Christine A. Hrycyna, Dirk H. Trauner, Mark D. Distefano
Rok vydání:	2022
Předmět:	Sphingolipids Saccharomyces cerevisiae Proteins Terpenes Protein Prenylation Membrane Proteins Metalloendopeptidases Saccharomyces cerevisiae General Medicine Lipids Biochemistry Pheromones Farnesyltranstransferase Molecular Medicine Peptides
Zdroj:	ACS Chemical Biology. 17:2945-2953
ISSN:	1554-8937 1554-8929
DOI:	10.1021/acschembio.2c00645
Popis:	Photoswitchable lipids have emerged as attractive tools for the optical control of lipid bioactivity, metabolism, and biophysical properties. Their design is typically based on the incorporation of an azobenzene photoswitch into the hydrophobic lipid tail, which can be switched between its
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeb19c92a26a6054aa394d5ecad65ed4 https://doi.org/10.1021/acschembio.2c00645 Zobrazit plný text záznamu