Polymorphisms of the tissue factor pathway inhibitor gene and the risk of restenosis after coronary angioplasty
| Autor: | Didier Moatti, Philippe Amouyel, D. de Prost, Véronique Ollivier, Aline Meirhaeghe, Christophe Bauters |
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| Rok vydání: | 2001 |
| Předmět: |
Male
medicine.medical_specialty Pathology medicine.medical_treatment Lipoproteins Coronary Disease HindIII Lower risk Coronary Restenosis Exon Tissue factor Tissue factor pathway inhibitor Restenosis Internal medicine Angioplasty Genotype medicine Humans Angioplasty Balloon Coronary Alleles Aged Polymorphism Genetic biology business.industry Hematology General Medicine Middle Aged medicine.disease Endocrinology biology.protein Female business |
| Zdroj: | Blood coagulationfibrinolysis : an international journal in haemostasis and thrombosis. 12(4) |
| ISSN: | 0957-5235 |
| Popis: | Intracoronary stent implantation is associated with a significantly lower risk of restenosis compared with balloon angioplasty. However, restenosis still occurs in some cases. Experimental studies suggest that the tissue factor pathway is involved in this phenomenon. We investigated a possible relationship between three previously identified polymorphisms of the tissue factor pathway inhibitor (TFPI) gene and restenosis in 443 patients who underwent angioplasty, with or without stent implantation. The effect of the intron 7-33T |
| Databáze: | OpenAIRE |
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