Postnatal exposure to predator odor (TMT) enhances spatial learning in mice adulthood
| Autor: | Gérard Brand, Romain Hacquemand, Laurence Jacquot |
|---|---|
| Přispěvatelé: | Laboratoire de Neurosciences Intégratives et Cliniques - UFC (EA 481) (NEURO), Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Centre National de la Recherche Scientifique (CNRS)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université de Franche-Comté (UFC), Institut National de la Recherche Agronomique (INRA)-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Neurosciences Intégratives et Cliniques - UFC ( NEURO ), Université Bourgogne Franche-Comté ( UBFC ) -Université de Franche-Comté ( UFC ), Centre des Sciences du Goût et de l'Alimentation [Dijon] ( CSGA ), Institut National de la Recherche Agronomique ( INRA ) -Université de Bourgogne ( UB ) -AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique ( CNRS ) |
| Rok vydání: | 2011 |
| Předmět: |
Male
[ SDV.AEN ] Life Sciences [q-bio]/Food and Nutrition Morris water navigation task Physiology MESH: Fear MESH : Analysis of Variance MESH: Animals Newborn MESH : Maze Learning Behavioral Neuroscience Mice 0302 clinical medicine MESH : Fear MESH : Female MESH: Animals Predator MESH: Avoidance Learning MESH : Avoidance Learning MESH : Animals Newborn 05 social sciences Fear MESH : Odors Memory Short-Term Female MESH : Space Perception Psychology Odors MESH : Male MESH: Space Perception MESH : Memory Short-Term Stimulus (physiology) MESH: Memory Short-Term 03 medical and health sciences Memory MESH: Analysis of Variance MESH : Mice Avoidance Learning Animals 0501 psychology and cognitive sciences 050102 behavioral science & comparative psychology Animal species Maze Learning MESH: Mice Analysis of Variance Radial arm maze MESH: Odors MESH: Maze Learning Newborn Physiological responses MESH: Male Odor Short-Term Animals Newborn Space Perception Odorants Spatial learning MESH : Animals Neuroscience MESH: Female [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition 030217 neurology & neurosurgery |
| Zdroj: | Behavioural Brain Research Behavioural Brain Research, Elsevier, 2012, 229 (1), pp.113-7. ⟨10.1016/j.bbr.2011.12.032⟩ Behavioural Brain Research, Elsevier, 2012, 229 (1), pp.113-7. 〈10.1016/j.bbr.2011.12.032〉 |
| ISSN: | 1872-7549 0166-4328 |
| DOI: | 10.1016/j.bbr.2011.12.032⟩ |
| Popis: | International audience; Adult behavioral and physiological responses are partly dependent on neonatal experiences. In several animal species, enriched/aprovished environments and stressful/appeasing events are crucial in the setting of adaptative behaviors. However, little is known about the effects of postnatal exposure to predator odor (as unconditioned fear-related stimulus) on spatial learning at adulthood. Thus, the aim of the present study was to investigate the effects of a postnatal exposure to 2,4,5-trimethylthiazoline (TMT, as a predator odor) on radial arm maze (RAM), Tolman maze (TM) and Morris water maze (MWM) in mice at adulthood. The results showed that a TMT group constituted by mice exposed postnatally during 3 weeks to TMT presented significantly better spatial learning achievements in adulthood compared to a water group, postnatally exposed to water only, as well as compared to a butanol group (butanol used as an odor without ecological significance) exposed postnatally to butanol during 3 weeks. |
| Databáze: | OpenAIRE |
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