Determination of phenolic and triterpenic compounds in Jatropha gossypiifolia L by Ultra-high performance liquid chromatography-tandem mass spectrometric (UHPLC-MS/MS)
| Autor: | Thaís Ramos Dal Molin, Carine Viana, Gabriela Camera Leal, Géssica Domingos da Silveira, Osmar Alves Lameira, Mariana Tatsch da Silva Souza, Rudinei da Silva Silveira, Luciana Assis Gobo, Leandro Machado de Carvalho, Henrique Faccin |
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| Přispěvatelé: | Rudinei da Silva Silveira, UFSM, Gabriela Camera Leal, UFSM, Thais Ramos Dal Molin, UFSM, Henrique Faccin, UFSM, Luciana Assis Gobo, UFSM, Géssica Domingos da Silveira, UFSM, Mariana Tatsch da Silva Souza, UFSM, OSMAR ALVES LAMEIRA, CPATU, Leandro Machado de Carvalho, UFSM, Carine Viana, UFSM. |
| Rok vydání: | 2020 |
| Předmět: |
Compostos fenólicos
Jatropha gossypiifolia 030226 pharmacology & pharmacy 01 natural sciences Flavones Ferulic acid 03 medical and health sciences chemistry.chemical_compound Pharmacy and materia medica 0302 clinical medicine Chlorogenic acid Jatropha gossypiifolia L Vanillic acid Caffeic acid Gallic acid chemistry.chemical_classification Chromatography biology Triterpenic compounds Planta Medicinal food and beverages biology.organism_classification Phenolic compounds 0104 chemical sciences RS1-441 010404 medicinal & biomolecular chemistry chemistry Pinhão roxo Polyphenol UHPLC-MS/MS |
| Zdroj: | Brazilian Journal of Pharmaceutical Sciences, Vol 56 (2020) Brazilian Journal of Pharmaceutical Sciences, Volume: 56, Article number: e17262, Published: 06 APR 2020 Repositório Institucional da EMBRAPA (Repository Open Access to Scientific Information from EMBRAPA-Alice) Empresa Brasileira de Pesquisa Agropecuária (Embrapa) instacron:EMBRAPA Brazilian Journal of Pharmaceutical Sciences; Vol. 56 (2020); e17262 Brazilian Journal of Pharmaceutical Sciences; v. 56 (2020); e17262 Brazilian Journal of Pharmaceutical Sciences Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 2175-9790 1984-8250 |
| Popis: | This work describes the chemical characterization of extracts of Jatropha gossypiifolia (from Amazonia region) concerning the presence of phenolic and triterpenic compounds using Ultra High Perfomance Liquid chromatography coupled to Mass Spectrometry in Tandem (UHPLC-MS/MS) methods. The studied compounds belong to the most frequently found classes in medicinal plants (triterpenes, flavonoids, flavones, hydroxycinnamic acids, coumarins, catechins and stilbenes), which have been analyzed as chemical and bioactive markers in hydroethanolic and aqueous extracts. Several polyphenolic compounds identified herein are unprecedented in the scientific literature for this species. The chemical markers identified and quantified in the studied extracts of J. gossypiifolia were gallic acid, chlorogenic acid, catechin, caffeic acid, vanillic acid, p-coumaric acid, ferullic acid, rutin, quercitrin, 3-acetylcoumarin, trans-cinnamic acid, quercetin, luteolin, apigenin, kaempferol, chrysin. α-amyrin, β-amyrin and lupeol. As the majority compounds, (+)-catechin, p-coumaric acid, ferulic acid, luteolin, α-amyrin and β-amyrin were found to be present at mg kg−1 levels. J. gossypiifolia extracts presented a high in vitro activity against different reactive oxygen species (hydroxyl, peroxyl, and superoxide anion radicals). Several polyphenolic compound data presented herein are unprecedented in the scientific literature for this plant species. As a result, this plant can be a new source of bioactive molecules for therapeutic purposes Made available in DSpace on 2020-04-15T01:01:41Z (GMT). No. of bitstreams: 1 21759790bjps56e17262.pdf: 519348 bytes, checksum: 80cca924293c1a262751331e6f7ccb27 (MD5) Previous issue date: 2020 |
| Databáze: | OpenAIRE |
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