Stilbenes from the roots of Pleuropterus ciliinervis and their antioxidant activities

Autor: Jae Gil Kim, Hyeong Kyu Lee, MinKyun Na, Ren Bo An, Jong Pill Lee, Sam Sik Kang, KiHwan Bae, Byung Sun Min, Sang Myung Lee
Rok vydání: 2003
Předmět:
Zdroj: Phytochemistry. 64:759-763
ISSN: 0031-9422
DOI: 10.1016/s0031-9422(03)00417-5
Popis: Two stilbene glycosides, pieceid-2″- O -gallate and pieceid-2″- O -coumarate, were isolated from the MeOH extract of the roots of Pleuropterus ciliinervis Nakai (Polygonaceae), together with two known compounds, resveratrol and pieceid. Their structures were determined spectroscopically, particularly by 2D NMR spectroscopic analysis. The antioxidant activities of stilbenes isolated were determined in vitro against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals, superoxide radicals and by determining their lipid peroxidation inhibitory activities. Among the compounds isolated, pieceid-2″- O -gallate had the most potent inhibitory scavenging effect on DPPH, superoxide radicals and upon lipid peroxidation inhibition with IC 50 values of 16.5, 23.9 and 5.1 μM, respectively.
Databáze: OpenAIRE